General
Preferred name
[3H]oxotremorine-M
Synonyms
OXOTREMORINE METHIODIDE ()
Oxotremorine M ()
Oxotremorine M (iodide) ()
[3H]oxotremorine-M ()
P&D ID
PD046884
CAS
3854-04-4
63939-65-1
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Oxotremorine-M is an orthosteric agonist of muscarinic acetylcholine receptors.
(GtoPdb)
DESCRIPTION
The position of the tritiated hydrogen is not specified in the available literature therefore we do not show it in our structure.
(GtoPdb)
DESCRIPTION
Potent, centrally active H2 antagonist
(Tocris Bioactive Compound Library)
DESCRIPTION
Nonselective muscarinic acetylcholine receptor agonist
(LOPAC library)
DESCRIPTION
Muscarinic agonist
(Tocriscreen Total)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
12
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Drug Repurposing Hub
DrugMAP
EU-OPENSCREEN Bioactive Compound Library
LOPAC library
MedChem Express Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Total
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
195.15
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
0
cLogP
0.32
TPSA
20.31
Fraction CSP3
0.73
Chiral centers
0.0
Largest ring
5.0
QED
0.46
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Muscarinic
Primary Target
Non-selective Muscarinics
MOA
Agonist
acetylcholine receptor agonist
Target
CHRM1, CHRM2, CHRM3, CHRM4
mAChR
Pathway
GPCR/G protein
Neuronal Signaling
Source data
