General
Preferred name
MOZAVAPTAN
Synonyms
OPC-31260 ()
OPC31260l ()
Mozavaptan (hydrochloride) ()
OPC-31260 (hydrochloride) ()
Mozavaptane ()
Mozavaptan-d6 ()
P&D ID
PD046836
CAS
137975-06-5
138470-70-9
2750534-83-7
Tags
available
drug
Approved by
PMDA
First approval
2006
Drug indication
Hyponatraemia
Drug Status
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
20
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
Ki Database
Mcule NIBR MoA Box Subset
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
38
Properties
(calculated by RDKit )
Molecular Weight
427.23
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
3
cLogP
5.29
TPSA
52.65
Fraction CSP3
0.26
Chiral centers
1.0
Largest ring
7.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Target
Vasopressin receptor 1
Vasopressin receptor 2
Vasopressin Receptor
Member status
member
MOA
Vasopressin (AVP) V2 Antagonists
Source data
