General
Preferred name
ONO-AE3-237
Synonyms
P&D ID
PD046686
Tags
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION ONO-AE3-237 has high DP1 antagonist selectivity and (sub)nanomolar affinity. (GtoPdb)
Compound Sets
6
Concise Guide to Pharmacology 2017/18
8537
Concise Guide to Pharmacology 2019/20
8537
Concise Guide to Pharmacology 2021/22
8537
Concise Guide to Pharmacology 2023/24
8537
DrugMAP
DMGA4W5
Guide to Pharmacology
8537
External IDs
7
Properties
(calculated by RDKit )
Molecular Weight
484.2
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
6
Ring Count
5
Aromatic Ring Count
4
cLogP
4.85
TPSA
81.0
Fraction CSP3
0.24
Chiral centers
1.0
Largest ring
6.0
QED
0.42
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Source data