General
Preferred name
BEFETUPITANT
Synonyms
Ro67-5930 ()
R-673 ()
RO 67-5930 ()
RO-67-5930 ()
RO-675930 ()
P&D ID
PD046617
CAS
290296-68-3
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Befetupitant is a potent and selective NK1 receptor antagonist. Befetupitant is potentially useful in controlling chemotherapy-induced nausea and vomiting.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
BOC Sciences Bioactive Compounds
ChEMBL Drugs
DrugMAP
Guide to Pharmacology
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
17
Molecular Weight
565.22
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
3
cLogP
6.87
TPSA
45.67
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.32
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Neurokinin Receptor
Pathway
Neuronal Signaling
GPCR/G protein
Source data
