General
Preferred name
aminopicoline
Synonyms
2-amino-4-methylpyridine ()
Ascensil ()
P&D ID
PD046611
CAS
695-34-1
135995-51-6
Tags
available
drug
Drug indication
Discovery agent
Drug Status
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Aminopicoline (Ascensil) is a potent and nonselective inhibitor of NO synthase (NOS) isoenzymes (iNOS, nNOS, eNOS)[1].
DESCRIPTION 2-Amino-4-methylpyridine is a selective inhibitor of neuronal nitric oxide synthase. (Enamine Bioactive Compounds)
Compound Sets
13
Concise Guide to Pharmacology 2017/18
5111
Concise Guide to Pharmacology 2019/20
5111
Concise Guide to Pharmacology 2021/22
5111
Concise Guide to Pharmacology 2023/24
5111
DrugCentral
172
DrugCentral Approved Drugs
172
DrugMAP
DM1OED2
DrugMatrix
Enamine Bioactive Compounds
EBC-03074
EU-OPENSCREEN Bioactive Compound Library
EOS102083
Guide to Pharmacology
5111
MedChem Express Bioactive Compound Library
HY-W003969
ReFrame library
External IDs
28
Properties
(calculated by RDKit )
Molecular Weight
108.07
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
1
Aromatic Ring Count
1
cLogP
0.97
TPSA
38.91
Fraction CSP3
0.17
Chiral centers
0.0
Largest ring
6.0
QED
0.54
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
NO Synthase
Pathway
Immunology/Inflammation
Source data