General
Preferred name
ABT-239
Synonyms
ABT 239 tartrate ()
P&D ID
PD046234
CAS
460746-46-7
460748-71-4
Tags
available
drug candidate
Drug indication
Cognitive impairment
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
ABT-239 is a novel, highly efficacious, non-imidazole class of H3R antagonist and a transient receptor potential vanilloid type 1 (TRPV1) antagonist.
PRICE
118
DESCRIPTION
ABT 239 tartrate is a potent and selective histamine H3 receptor antagonist or inverse agonist.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
ABT-239 is a novel, highly efficacious non-imidazole class histamine H3 receptor (H3R) antagonist and also acts as a transient receptor potential vanilloid type 1 (TRPV1) antagonist.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
Axon Medchem Screening Library
BOC Sciences Bioactive Compounds
Drug Repurposing Hub
DrugMAP
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
30
Molecular Weight
330.17
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
3
cLogP
5.0
TPSA
40.17
Fraction CSP3
0.32
Chiral centers
1.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Histamine Receptor
TRP Channel
TRPV1
HRH1, HRH2, HRH3
H3 antagonist
MOA
Histamine Receptor antagonist
Pathway
GPCR/G protein
Immunology/Inflammation
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data
