General
Preferred name
NF340
Synonyms
NF 340 ()
P&D ID
PD046230
CAS
202982-98-7
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION NF 340 is a selective P2Y11 antagonist. It shows competitive antagonism against ATPĪ³S with pIC50 values of 6.43 and 7.14 in Ca2+ and cAMP assays respectively. (BOC Sciences Bioactive Compounds)
Compound Sets
7
BOC Sciences Bioactive Compounds
nf-340-cas-202982-98-7-item-169491
Concise Guide to Pharmacology 2017/18
1762
Concise Guide to Pharmacology 2019/20
1762
Concise Guide to Pharmacology 2021/22
1762
Concise Guide to Pharmacology 2023/24
1762
DrugMAP
DMPSXR8
Guide to Pharmacology
1762
External IDs
9
Properties
(calculated by RDKit )
Molecular Weight
985.99
Hydrogen Bond Acceptors
15
Hydrogen Bond Donors
4
Rotatable Bonds
14
Ring Count
6
Aromatic Ring Count
6
cLogP
3.91
TPSA
272.81
Fraction CSP3
0.05
Chiral centers
0.0
Largest ring
6.0
QED
0.11
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Source data