General
Preferred name
TUBERCIDIN
Synonyms
Sparsomycin A ()
7-Deazaadenosine ()
P&D ID
PD046183
CAS
69-33-0
Tags
available
natural product
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 49
DESCRIPTION Tubercidin is an analogue of . It was originally isolated from the soil-dwelling actinomycete Streptomyces tubercidicus and demonstrates antineoplastic and broad-spectrum antimicrobial activities . (GtoPdb)
DESCRIPTION Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities. (TargetMol Bioactive Compound Library)
Cell lines
22
Organisms
9
Compound Sets
11
Cayman Chemical Bioactives
35834
Concise Guide to Pharmacology 2017/18
4755
Concise Guide to Pharmacology 2019/20
4755
Concise Guide to Pharmacology 2021/22
4755
Concise Guide to Pharmacology 2023/24
4755
Concise Guide to Pharmacology 2025/26
4755
DrugBank
DB03172
DrugMAP
DMHICK8
Guide to Pharmacology
4755
ReFrame library
TargetMol Bioactive Compound Library
T7004
External IDs
45
Properties
(calculated by RDKit )
Molecular Weight
266.1
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
-1.38
TPSA
126.65
Fraction CSP3
0.45
Chiral centers
4.0
Largest ring
6.0
QED
0.53
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
DNA/RNA Synthesis
Influenza Virus
MOA
DNA/RNA Synthesis inhibitor
Pathway
Cell Cycle/Checkpoint
DNA Damage/DNA Repair
Microbiology/virology
Source data