General
Preferred name
Butaclamol
Synonyms
(±)-Butaclamol hydrochloride ()
(+)-Butaclamol hydrochloride ()
(+)-butaclamol ()
BUTACLAMOL HYDROCHLORIDE ()
AY 23,028 ()
AY-23,028 ()
AY 23028 ()
Butaclamol hcl ()
AY-23028 ()
P&D ID
PD046177
CAS
36504-94-6
36504-93-5
55528-07-9
56245-67-1
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
One of the two enantiomers found in the INN-assigned racemic compound butaclamol.
(GtoPdb)
DESCRIPTION
Dopamine receptor antagonist; selective for D2 over D1
(LOPAC library)
DESCRIPTION
Dopamine receptor antagonist
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
6
ChEMBL Drugs
Drug Repurposing Hub
DrugMAP
Guide to Pharmacology
LOPAC library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
28
Molecular Weight
361.24
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
5
Aromatic Ring Count
2
cLogP
4.84
TPSA
23.47
Fraction CSP3
0.52
Chiral centers
3.0
Largest ring
7.0
QED
0.73
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
D2>D1
Target
DRD1, DRD2, DRD3, DRD4, DRD5, HTR1A, HTR2A
MOA
Dopamine Receptor antagonist
Source data
