General
Preferred name
DOTHIEPIN HYDROCHLORIDE
Synonyms
Dosulepin hydrochloride ()
Dothiepin hcl ()
Thaden ()
Prothiaden ()
Dothep ()
Ken-Pro ()
Dopress ()
Prepadine ()
Dothapax 75 ()
NSC-172130 ()
Dothapax 25 ()
P&D ID
PD045835
CAS
25627-36-5
897-15-4
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Antidepressant
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
14
Properties
(calculated by RDKit )
Molecular Weight
331.12
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
2
cLogP
5.1
TPSA
3.24
Fraction CSP3
0.26
Chiral centers
0.0
Largest ring
7.0
QED
0.77
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
