General
Preferred name
Sulforaphene
Synonyms
L-Sulforaphene ()
P&D ID
PD045805
CAS
592-95-0
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF©\¦ÊB and other signals[1][2][3][4].
PRICE 58
DESCRIPTION Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF???B and other signals.
DESCRIPTION Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals. (TargetMol Bioactive Compound Library)
Cell lines
5
Organisms
0
Compound Sets
4
Cayman Chemical Bioactives
17152
MedChem Express Bioactive Compound Library
HY-N2450
Selleckchem Bioactive Compound Library
sulforaphene
TargetMol Bioactive Compound Library
TL0016
External IDs
23
Properties
(calculated by RDKit )
Molecular Weight
175.01
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
0
Aromatic Ring Count
0
cLogP
1.37
TPSA
35.42
Fraction CSP3
0.5
Chiral centers
1.0
Largest ring
0.0
QED
0.28
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Apoptosis
EGFR
ERK
NF-κB
Microtubule/Tubulin
ROS, Bcl-2, NF-¦ÊB, EGFR, ERK
Pathway
NF-¦ÊB
Cell Cycle/DNA Damage
cytoskeleton
JAK/STAT Signaling
MAPK/ERK Pathway
Protein Tyrosine Kinase/RTK
Stem Cell/Wnt
Angiogenesis
MAPK
Tyrosine Kinase/Adaptors
Source data