General
Preferred name
METHANTHELINE BROMIDE
Synonyms
Methanthelinium Bromide ()
Banthine ()
Vagantin ()
Bromure de methanthelinium ()
NSC-32145 ()
Bromuro de metantelinio ()
P&D ID
PD045754
CAS
53-46-3
Tags
available
drug
Drug Status
approved
Max Phase
4.0
First approval
1951
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Methantheline bromide is an antimuscarinic. It is a strong muscarinic receptor blocking drug used in the treatment of overactive bladder syndrome, hypersalivation and hyperhidrosis. It is a synthetic antispasmodic and is used to relieve cramps or spasms of the stomach, bladder and intestines. It is also used to treat pancreatitis, biliary dyskinesia, gastritis or urinary problems. It has been listed.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
DrugMatrix
Prestwick Chemical Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Molecular Weight
419.11
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
2
cLogP
0.96
TPSA
35.53
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Solubility
Soluble in DMSO, not in water
Source data
