General
Preferred name
Glafenine HCl
Synonyms
Glafenine hydrochloride ()
Glafenine (hydrochloride) ()
Glafenin hydrochloride ()
P&D ID
PD045581
CAS
65513-72-6
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Glafenine hydrochloride is a non-narcotic analgesic and non-steroidal anti-inflammatory drug. It is an ABCG2 inhibitor with an IC50 of 3.2 ¦ÌM. Glafenine can also antagonize the misfolding of SLC4A11 protein[1].
DESCRIPTION
Glafenine Hydrochloride is an anti-inflammatory agent.
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
14
Molecular Weight
408.06
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
3
cLogP
3.56
TPSA
91.68
Fraction CSP3
0.16
Chiral centers
1.0
Largest ring
6.0
QED
0.54
QED
0.54
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Target
Apoptosis
CFTR
COX
Endoplasmic Reticulum Oxidoreductase 1 (ERO1)
Anion Exchangers
Pathway
Anti-infection
Immunology/Inflammation
Membrane Transporter/Ion Channel
Source data
