General
Preferred name
Lucerastat
Synonyms
NB-DGJ ()
N-(n-Butyl)deoxygalactonojirimycin ()
ACT-434964 ()
N-N-Butyl Deoxygalactonojirimycin ()
P&D ID
PD044360
CAS
141206-42-0
Tags
drug candidate
natural product
available
Drug Status
investigational
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
Mcule NIBR MoA Box Subset
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
23
Properties
(calculated by RDKit )
Molecular Weight
219.15
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
4
Rotatable Bonds
4
Ring Count
1
Aromatic Ring Count
0
cLogP
-1.45
TPSA
84.16
Fraction CSP3
1.0
Chiral centers
4.0
Largest ring
6.0
QED
0.46
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
member
MOA
Ceramide Glucosyltransferase Inhibitors
Pathway
Neuronal Signaling
Target
Glucosylceramide Synthase (GCS)
Source data
