General
Preferred name
Curvulin
Synonyms
P&D ID
PD044261
CAS
19054-27-4
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Curvulin is a phytotoxin[1]. Curvularin inhibits microtubule assembly and inhibits iNOS expression.
PRICE
324
DESCRIPTION
Curvulin is a phytotoxin that is first isolated from several species of the mold Curvularia. Curvulin inhibits microtubule assembly and has also been proved to inhibit iNOS expression.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
MedChem Express Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
13
Molecular Weight
238.08
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
1
Aromatic Ring Count
1
cLogP
1.41
TPSA
83.83
Fraction CSP3
0.33
Chiral centers
0.0
Largest ring
6.0
QED
0.61
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Microtubule/Tubulin
Microtubule
Pathway
Cell Cycle/DNA Damage
cytoskeleton
Cytoskeletal Signaling
Source data
