General
Preferred name
DELAFLOXACIN
Synonyms
ABT492 meglumine ()
WQ-3034 meglumine ()
RX-3341 meglumine ()
ABT492 ()
WQ-3034 ()
RX-3341 ()
ABT-492 ()
ABT 492 meglumine ()
DELAFLOXACIN MEGLUMINE ()
Delafloxacin (meglumine) ()
RX-3341J, WQ-3034 ()
ABT-492, RX-3341, WQ-3034, Baxdela ()
Delafloxacin (ABT-492) ()
Delafloxacino ()
Delafloxacine ()
ABT-492 MEGLUMINE ()
Quofenix ()
Baxdela ()
WQ-3034 AND ABT-492 ()
P&D ID
PD044134
CAS
189279-58-1
352458-37-8
339591-82-1
Tags
available
drug
Approved by
FDA
EMA
First approval
2017
Drug indication
Skin disease
Skin infection
gonorrhea
Bacterial infection
Acute bacterial skin infection
Drug Status
approved
investigational
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Delafloxacin is a fourth generation fluoroquinolone class antibacterial. It has a good spectum of activity against gram-positive bacteria and some atypical pathogens. (GtoPdb)
DESCRIPTION Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia[1].
PRICE 32
DESCRIPTION Delafloxacin (WQ-3034) (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent. It has potent inhibitory against levofloxacin-resistant Streptococcus pneumoniae strains (MIC: 0.0078-0.125 ??g/ml).
DESCRIPTION Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia[1].
PRICE 40
DESCRIPTION Delafloxacin is a fluoroquinolone antibiotic that demonstrates extremely high potency against a wide range of bacteria in vitro, including levofloxacin-resistant strains of S. pneumoniae and methicillin-resistant S. aureus. It has an anionic structure, which enhances its potency in acidic environments and in skin and soft tissue infections. (BOC Sciences Bioactive Compounds)
DESCRIPTION Delafloxacin (WQ-3034) (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent. It has potent inhibitory against levofloxacin-resistant Streptococcus pneumoniae strains (MIC: 0.0078-0.125 μg/ml). (TargetMol Bioactive Compound Library)
DESCRIPTION Delafloxacin meglumine (RX-3341 meglumine) is a broad-spectrum fluoroquinolone antibiotic. (TargetMol Bioactive Compound Library)
Compound Sets
18
AdooQ Bioactive Compound Library
A10023
A15064
BOC Sciences Bioactive Compounds
delafloxacin-cas-189279-58-1-292324
Cayman Chemical Bioactives
20314
27935
ChEMBL Approved Drugs
CHEMBL2105637
CHEMBL2105638
ChEMBL Drugs
CHEMBL2105637
CHEMBL2105638
Drug Repurposing Hub
DrugBank
DB11943
DrugBank Approved Drugs
DB11943
DrugCentral
5238
DrugCentral Approved Drugs
5238
DrugMAP
DMJFD2I
DMVTU5Q
DrugMAP Approved Drugs
DMVTU5Q
Guide to Pharmacology
10799
MedChem Express Bioactive Compound Library
HY-14814
HY-14814A
NCATS Inxight Approved Drugs
6315412YVF
ReFrame library
Selleckchem Bioactive Compound Library
ABT-492
delafloxacin-meglumine
TargetMol Bioactive Compound Library
T4063
T8173
External IDs
48
Properties
(calculated by RDKit )
Molecular Weight
440.05
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
3
cLogP
1.92
TPSA
121.68
Fraction CSP3
0.17
Chiral centers
0.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
Antibiotics
MOA
antiinfective drug
Pathway
Microbiology/virology
Anti-infection
Source data