General
Preferred name
Barnidipine (hydrochloride)
Synonyms
Barnidipine hydrochloride ()
Mepirodipine (hydrochloride) ()
YM-09730-5 ()
P&D ID
PD044055
CAS
104713-75-9
104757-53-1
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Barnidipine (Mepirodipine) hydrochloride is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki = 0.21 nmol/L, has selective action against CaA receptors. Barnidipine hydrochloride is an orally active antihypertensive agent that can reduce the level of platelet-derived growth factor B-chain mRNA and peripheral vascular resistance[1][2][3][4].
Compound Sets
3
Axon Medchem Screening Library
3014
Cayman Chemical Bioactives
20448
MedChem Express Bioactive Compound Library
HY-107322
External IDs
18
Properties
(calculated by RDKit )
Molecular Weight
527.18
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
2
cLogP
4.24
TPSA
111.01
Fraction CSP3
0.33
Chiral centers
2.0
Largest ring
6.0
QED
0.32
QED
0.32
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Ca channel blocker
Calcium Channel
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data