General
Preferred name
AS8351
Synonyms
NSC 51355 ()
NSC51355 ()
AS-8351 ()
P&D ID
PD043683
CAS
796-42-9
Tags
available
nuisance
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION AS8351 (NSC51355) is a KDM5B inhibitor, which can induce and sustain active chromatin marks to facilitate the induction of cardiomyocyte-like cells[1].
Cell lines
3
Organisms
1
Compound Sets
5
A Collection of Useful Nuisance Compounds (CONS) for Interrogation of Bioassay Integrity
Cayman Chemical Bioactives
20811
MedChem Express Bioactive Compound Library
HY-100744
Nuisance compounds in cellular assays
Selleckchem Bioactive Compound Library
as-8351
External IDs
14
Properties
(calculated by RDKit )
Molecular Weight
291.1
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
3
cLogP
2.7
TPSA
74.58
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.58
Structural alerts
1
Chelation
Fe
Nuisance compounds
Related compounds
Custom attributes
(extracted from source data)
MOA
Others inhibitor
Target
Demethylase
Histone Demethylase
Pathway
Epigenetics
Nuisance MOA
Chelation
Targets
KDM5B
Source data