General
Preferred name
DIMBOA
Synonyms
2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one ()
P&D ID
PD042747
CAS
15893-52-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION DIMBOA, an antibiotic, has antibacterial properties and inhibits bacteria such as Staphylococcus aureus and the mycotoxin-producing fungus Fusarium graminearum (which causes scab). DIMBOA exhibits strong free radical scavenging activity and weak iron(III) ion reducing activity, and has antioxidant activity. DIMBOA inhibits the biosynthesis and accumulation of toxic trichothecenes by affecting the expression of Tri6 and Tri5. DIMBOA reduces plant susceptibility to scab. DIMBOA also exhibits cytotoxicity to plant cells, causing plasmolysis, cell collapse, and cell rupture[1][2][3][4][5].
PRICE 58
DESCRIPTION Dimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal compound used in crops. (TargetMol Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
39647
MedChem Express Bioactive Compound Library
HY-N7432
TargetMol Bioactive Compound Library
T22308
External IDs
28
Properties
(calculated by RDKit )
Molecular Weight
211.05
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
1
cLogP
0.13
TPSA
79.23
Fraction CSP3
0.22
Chiral centers
1.0
Largest ring
6.0
QED
0.65
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology/virology
Anti-infection
Target
antibiotic
Bacterial
Fungal
Source data