General
Preferred name
APHIDICOLIN
Synonyms
(+)-Aphidicolin ()
P&D ID
PD041796
CAS
38966-21-1
Tags
available
drug candidate
nuisance
natural product
Drug Status
investigational
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
4
Organisms
1
Compound Sets
9
Cayman Chemical Bioactives
Drug Repurposing Hub
DrugBank
DrugMAP
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
Nuisance compounds in cellular assays
Reference compounds for characterizing cellular injury in high-content cellular morphology assays
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
33
Properties
(calculated by RDKit )
Molecular Weight
338.25
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
2.09
TPSA
80.92
Fraction CSP3
1.0
Chiral centers
8.0
Largest ring
6.0
QED
0.62
Structural alerts
1
Genotoxic
Nuisance compounds in cellular assays
Related compounds
Custom attributes
(extracted from source data)
Member status
member
MOA
Inhibitor of DNA polymerase alpha
DNA polymerase alpha inhibitor
RNA synthesis inhibitor
Cellular injury category
Genotoxin
Pathway
Anti-infection
Apoptosis
Cell Cycle/DNA Damage
Target
antibiotic
DNA/RNA Synthesis
HSV
Orthopoxvirus
Source data
