General
Preferred name
DELTAMETHRIN
Synonyms
decamethrin ()
P&D ID
PD041203
CAS
52918-63-5
Tags
available
drug
Drug Status
approved
experimental
Drug indication
Parasitic infection
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Deltamethrin (Decamethrin) is an orally active synthetic pyrethroid insecticide. Deltamethrin induces oxidative stress and results in inflammation and apoptosis via inhibiting Nrf2/HO-1 pathway. Deltamethrin has an anticancer effect by inducing apoptosis. Deltamethrin can be used extensively in pest control[1][2][3][4][5][6].
Compound Sets
8
Cayman Chemical Bioactives
24172
ChEMBL Drugs
CHEMBL1593566
DrugBank
DB13600
DrugCentral
4378
DrugCentral Approved Drugs
4378
MedChem Express Bioactive Compound Library
HY-B1971
Selleckchem Bioactive Compound Library
deltamethrin
VGSC-DB
NA6054
External IDs
34
Properties
(calculated by RDKit )
Molecular Weight
502.97
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
2
cLogP
6.49
TPSA
59.32
Fraction CSP3
0.27
Chiral centers
3.0
Largest ring
6.0
QED
0.42
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Apoptosis
Bcl-2 Family
Calcium Channel
Caspase
Endogenous Metabolite
Interleukin Related
NF-κB
VGSC Target
Nav1.8
Pathway
Immunology/Inflammation
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-¦ÊB
Source data