General
Preferred name
CALCIUM DOBESILATE
Synonyms
Doxium 500 ()
Dobesilate de calcium ()
Dobesilato de calcio ()
Dobesilate calcium ()
Dexium ()
205 E ()
205-E ()
Hydroquinone calcium sulfonate ()
Doxium ()
P&D ID
PD040317
CAS
20123-80-2
Tags
available
drug candidate
Drug Status
investigational
Max Phase
3.0
Drug indication
Infertility
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Calcium dobesilate is a vascular protector with oral activity that can clear hydroxyl free radicals, with an IC50 of 1.1 pM. Calcium dobesilate has antioxidant activity and helps to reduce oxidative stress and inflammation in the retinas of diabetic mice. Calcium dobesilate can be used to study chronic venous diseases, diabetic retinopathy, and the occurrence of hemorrhoids, among other conditions[1][2][3].
PRICE
29
DESCRIPTION
Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
ChEMBL Drugs
MedChem Express Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
18
Molecular Weight
417.93
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
2
cLogP
-0.38
TPSA
195.32
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.28
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Apoptosis
Source data
