General
Preferred name
PD039682
Synonyms
4'-bromo-Resveratrol ()
4′‐BR ()
4¡ä©\BR ()
P&D ID
PD039682
CAS
1224713-90-9
Tags
available
nuisance
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 4'-Bromo-resveratrol is a potent and dual inhibitor Sirtuin-1 and Sirtuin-3. 4'-Bromo-resveratrol inhibits melanoma cell growth through mitochondrial metabolic reprogramming. 4'-Bromo-resveratrol imparts antiproliferative effects in melanoma cells through a metabolic reprogramming and affecting the cell cycle and apoptosis signaling[1].
PRICE 74
DESCRIPTION 4'-Bromo-resveratrol is a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3). (BOC Sciences Bioactive Compounds)
DESCRIPTION 4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3) (TargetMol Bioactive Compound Library)
Compound Sets
5
BOC Sciences Bioactive Compounds
5-e-2-4-bromophenyl-vinyl-benzene-1-3-diol-cas-1224713-90-9-item-269278
Cayman Chemical Bioactives
20541
MedChem Express Bioactive Compound Library
HY-124113
Nuisance compounds in cellular assays
TargetMol Bioactive Compound Library
T21679
External IDs
11
Properties
(calculated by RDKit )
Molecular Weight
289.99
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
2
cLogP
4.03
TPSA
40.46
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.82
Structural alerts
1
Nonspecific/NOS
Resveratrols
Nuisance compounds
Custom attributes
(extracted from source data)
Target
SIRT1
SIRT3
Apoptosis
Sirtuin
Pathway
Cell Cycle/DNA Damage
Epigenetics
Chromatin/Epigenetic
DNA Damage/DNA Repair
Source data