General
Preferred name
cis-urocanic acid
Synonyms
cis-UCA ()
(Z)-Imidazole-4-acrylic acid ()
(Z)-Urocanic acid ()
(E)-Urocanic acid ()
(Z)-3-(1H-Imidazol-5-yl)acrylic acid ()
Imidazole-4-acrylic acid, (z)- ()
NSC-407934 ()
Urocanic acid, cis- ()
P&D ID
PD039374
CAS
7699-35-6
Tags
available
drug candidate
Drug Status
investigational
Max Phase
1.0
Drug indication
dry eye syndrome
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
326
DESCRIPTION
cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
ChEMBL Drugs
MedChem Express Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
18
Molecular Weight
138.04
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
0.51
TPSA
65.98
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
5.0
QED
0.58
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
5-HT2A Receptor
5-HT Receptor
Pathway
GPCR/G protein
Neuronal Signaling
Neuroscience
Source data
