General
Preferred name
O-DESMETHYL TRAMADOL
Synonyms
CHEMBL1400 ()
O-Desmethyltramadol ()
O-Desmethyl-cis-tramadol (hydrochloride) ()
O-Desmethyl-cis-tramadol (hydrochloride) (CRM) ()
O-Desmethyl-cis-tramadol-d6 (hydrochloride) (CRM) ()
P&D ID
PD039330
CAS
148262-77-5
144830-14-8
185453-02-5
1261393-87-6
Tags
available
probe
drug candidate
biased GPCR ligand
Drug indication
Discovery agent
Probe info
Probe type
calculated probe
Probe sources
Tool Compound Set
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
3
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
BiasDB
DrugMAP
LSP-MoA library (Laboratory of Systems Pharmacology)
ReFrame library
Tool Compound Set
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
37
Properties
(calculated by RDKit )
Molecular Weight
249.17
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
1
cLogP
2.33
TPSA
43.7
Fraction CSP3
0.6
Chiral centers
2.0
Largest ring
6.0
QED
0.86
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Mu opioid receptor
Source data
