General
Preferred name
PD033262
Synonyms
6-Chloropurine riboside ()
P&D ID
PD033262
CAS
5399-87-1
7596-60-3
2004-06-0
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION 6-Chloropurine riboside (6-CPR) is a purine nucleoside analog that has been found to have a wide range of biological activities. It inhibits the growth of tumor cells and induces apoptosis. It has also been shown to have anti-inflammatory, antiviral and antifungal properties. It has also been found to be neuroprotective and has been used in the treatment of neurological disorders.
DESCRIPTION (2R,3R,4S,5R)-2-(6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol is an inhibitor of adenosine kinase. (Enamine Bioactive Compounds)
Cell lines
0
Organisms
2
Compound Sets
3
Axon Medchem Screening Library
2417
Cayman Chemical Bioactives
36002
Enamine Bioactive Compounds
EBC-13852
External IDs
36
Properties
(calculated by RDKit )
Molecular Weight
286.05
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
-0.91
TPSA
113.52
Fraction CSP3
0.5
Chiral centers
4.0
Largest ring
6.0
QED
0.61
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Building block
Source data