General
Preferred name
(S)-methoprene
Synonyms
METHOPRENE (S) ()
METHOPRENE ()
ZR-515 ()
ZR2458 ()
ZR 2458 ()
ZR-2458 ()
(+)-Methoprene ()
Preco ()
S-Methoprene ()
(7S)-Methoprene ()
S-(+)-methoprene ()
(S)-(+)-Methoprene ()
Kabat ()
Apex ()
Zodiac ()
Metopreno ()
Dianex ()
Manina ()
Metoprag 20ce ()
Juvemon ()
ENT-70460 ()
ZPA-1019 ()
SB-515 ()
NSC-758655 ()
P&D ID
PD029296
CAS
52020-07-2
36557-27-4
65733-16-6
40596-69-8
Tags
available
drug
Drug Status
vet_approved
approved
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION S-Methoprene is an insect juvenile hormone analog and effective insecticide that blocks the transition from pupa to adult. S-Methoprene is also a CB(1) receptor ligand and inhibits the binding of the CB1 receptor antagonist [3H]CP-55940 to the CB1 receptor (IC50: 19.31 ¦ÌM)[1][2].
PRICE 30
DESCRIPTION Methoprene, an insect juvenile growth hormone mimic, is a growth-regulating insecticide that manifests its toxicity to target organisms by acting as a juvenile hormone agonist[1][2].
PRICE 29
DESCRIPTION S-Methoprene (ZR2458) is an analog of juvenile hormone and can be used as an insecticide. S-Methoprene alters redox activity of cytochrome oxidase and induces male sex differentiation. (TargetMol Bioactive Compound Library)
DESCRIPTION Methoprene (ZR-515) is a juvenile hormone (JH) mimic and a biological pesticide. Methoprene acts as an insect growth regulator interfering with the lifecycles of insects and preventing insects from reaching maturity or reproducing. (TargetMol Bioactive Compound Library)
Compound Sets
11
Cayman Chemical Bioactives
16807
ChEMBL Drugs
CHEMBL1875086
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DB11495
DrugBank Approved Drugs
DB11495
MedChem Express Bioactive Compound Library
HY-B1161A
HY-B1161
NPC Screening Collection
Selleckchem Bioactive Compound Library
methoprene
TargetMol Bioactive Compound Library
T19752
T16044
The Spectrum Collection
External IDs
51
Properties
(calculated by RDKit )
Molecular Weight
310.25
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
10
Ring Count
0
Aromatic Ring Count
0
cLogP
5.06
TPSA
35.53
Fraction CSP3
0.74
Chiral centers
1.0
Largest ring
0.0
QED
0.32
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Insecticide
Cannabinoid Receptor
Pathway
GPCR/G protein
Neuronal Signaling
Source data