General
Preferred name
[3H]CCPA
Synonyms
2-Chloro-N6-cyclopentyladenosine ()
[3H]CCPA ()
2-chloro-N6-Cyclopentyladenosine (hydrate) ()
2-chloro-N6-Cyclopentyladenosine ()
P&D ID
PD021806
CAS
37739-05-2
1217443-91-8
Tags
drug candidate
natural product
biased GPCR ligand
available
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Potent, selective A1 agonist (Tocriscreen Plus)
DESCRIPTION Non-selective adenosine A2 receptor agonist (Tocris Bioactive Compound Library)
DESCRIPTION Potent, selective A1 agonist (Tocriscreen Total)
Compound Sets
12
BiasDB
CCPA
Cayman Chemical Bioactives
28731
36477
Concise Guide to Pharmacology 2017/18
374
379
Concise Guide to Pharmacology 2019/20
374
379
Concise Guide to Pharmacology 2021/22
374
379
Concise Guide to Pharmacology 2023/24
374
379
Drug Repurposing Hub
DrugMAP
DMHDGB3
Guide to Pharmacology
374
379
Tocris Bioactive Compound Library
1705
Tocriscreen Plus
1705
Tocriscreen Total
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
369.12
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
4
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
2
cLogP
0.45
TPSA
125.55
Fraction CSP3
0.67
Chiral centers
4.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
7-TM Receptors
Primary Target
Adenosine A1 Receptors
MOA
Agonist
Adenosine Receptor agonist
Target
ADORA1, ADORA2A, ADORA2B, ADORA3
Source data