General
Preferred name
NNC 63-0532
Synonyms
P&D ID
PD021799
CAS
250685-44-0
Tags
available
biased GPCR ligand
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Potent non-peptide NOP agonist; brain penetrant
(Tocriscreen Plus)
DESCRIPTION
Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin
(Tocris Bioactive Compound Library)
DESCRIPTION
Potent non-peptide NOP agonist; brain penetrant
(Tocriscreen Total)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
BiasDB
Novartis Chemogenetic Library (NIBR MoA Box)
Tocris Bioactive Compound Library
Tocriscreen Plus
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
12
Molecular Weight
443.22
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
5
Aromatic Ring Count
3
cLogP
3.65
TPSA
53.09
Fraction CSP3
0.33
Chiral centers
0.0
Largest ring
6.0
QED
0.56
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
7-TM Receptors
Primary Target
NOP Receptors
MOA
Agonist
OPRL1 agonist
Member status
virtual
Source data
