General
Preferred name
Co 102862
Synonyms
V 102862 ()
V-102862 ()
P&D ID
PD021686
CAS
181144-66-1
Tags
available
drug candidate
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Co 102862 (V 102862) is a potent, broad-spectrum, state-dependent Na+ channel blocker. Co 102862 is also an orally active anticonvulsant[1].
PRICE 46
DESCRIPTION KV7.1 channel activator, activates IKs (Tocris Bioactive Compound Library)
DESCRIPTION State-dependent Na+ channel blocker; anticonvulsant (Tocriscreen Total)
DESCRIPTION Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies. (TargetMol Bioactive Compound Library)
Compound Sets
9
Cayman Chemical Bioactives
42437
Drug Repurposing Hub
DrugMAP
DMR2EUV
MedChem Express Bioactive Compound Library
HY-108504
ReFrame library
TargetMol Bioactive Compound Library
T22675
Tocris Bioactive Compound Library
2642
Tocriscreen Total
ZINC Tool Compounds
ZINC000000006785
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
273.09
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
2
cLogP
2.62
TPSA
76.71
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Voltage-gated sodium channel
SCN4A, SCN9A
Sodium Channel
Primary Target
Voltage-gated Sodium (NaV) Channels
MOA
Blocker
Sodium Channel blocker
Pathway
Membrane Transporter/Ion Channel
Source data