General
Preferred name
Co 102862
Synonyms
V-102862 ()
V 102862 ()
P&D ID
PD021686
CAS
181144-66-1
Tags
available
drug candidate
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
KV7.1 channel activator, activates IKs
(Tocris Bioactive Compound Library)
DESCRIPTION
State-dependent Na+ channel blocker; anticonvulsant
(Tocriscreen Total)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
Drug Repurposing Hub
DrugMAP
MedChem Express Bioactive Compound Library
ReFrame library
Tocris Bioactive Compound Library
Tocriscreen Total
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
14
Molecular Weight
273.09
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
2
cLogP
2.62
TPSA
76.71
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Voltage-gated Sodium (NaV) Channels
MOA
Blocker
Sodium Channel blocker
Target
SCN4A, SCN9A
Sodium Channel
Pathway
Membrane Transporter/Ion Channel
Source data
