General
Preferred name
LY2119620
Synonyms
LY 2119620 ()
LY-2119620 ()
P&D ID
PD021557
CAS
886047-22-9
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Selective positive allosteric modulator of M4 receptors; active in vivo; antipsychotic (Tocris Bioactive Compound Library)
DESCRIPTION LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors. (BOC Sciences Bioactive Compounds)
Compound Sets
13
AdooQ Bioactive Compound Library
A14217
BOC Sciences Bioactive Compounds
ly2119620-cas-886047-22-9-item-84-463475
Cayman Chemical Bioactives
26373
Concise Guide to Pharmacology 2017/18
6938
Concise Guide to Pharmacology 2019/20
6938
Concise Guide to Pharmacology 2021/22
6938
Concise Guide to Pharmacology 2023/24
6938
DrugMAP
DM4IELQ
Guide to Pharmacology
6938
MedChem Express Bioactive Compound Library
HY-15885
Selleckchem Bioactive Compound Library
ly2119620
TargetMol Bioactive Compound Library
T6575
Tocris Bioactive Compound Library
6964
External IDs
14
Properties
(calculated by RDKit )
Molecular Weight
437.13
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
2
cLogP
1.89
TPSA
100.79
Fraction CSP3
0.53
Chiral centers
0.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
Neuroscience
GPCR/G protein
Neuronal Signaling
Target
M2 mAChR
M4 mAChR
mAChR
AChR
Primary Target
M2 Receptors
MOA
AChR agonist
Modulator
Source data