General
Preferred name
ULIPRISTAL
Synonyms
CDB-3236 ()
Deacetyl CDB-2914 ()
Ulipristal acetate ulipristal ()
Uliprisnil ()
P&D ID
PD021543
CAS
159811-51-5
Tags
available
drug
Drug indication
Contraception
leiomyoma
Drug Status
investigational
approved
Max Phase
3.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
ABSORPTION Tmax, healthy subjects, single oral dose = 60-90 minutes;; Cmax, healthy subjects, single oral dose = 176 ± 89 ng/mL;; AUC(0-∞), healthy subjects, single oral dose = 556 ± 260 ng·h/mL;;
DESCRIPTION Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system[1].
PRICE 65
DESCRIPTION Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure. (TargetMol Bioactive Compound Library)
Compound Sets
8
ChEMBL Drugs
CHEMBL2103846
DrugBank
DB08867
DrugBank Approved Drugs
DB08867
DrugMAP
DMBNI20
DrugMAP Approved Drugs
DMBNI20
MedChem Express Bioactive Compound Library
HY-14959
NCATS Inxight Approved Drugs
6J5J15Q2X8
TargetMol Bioactive Compound Library
T6713
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
433.26
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
5
Aromatic Ring Count
1
cLogP
4.97
TPSA
57.61
Fraction CSP3
0.57
Chiral centers
5.0
Largest ring
6.0
QED
0.73
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
PR
Progesterone Receptor
Pathway
Vitamin D Related/Nuclear Receptor
Endocrinology/Hormones
Source data