General
Preferred name
ABSCISIC ACID
Synonyms
Abscisin II ()
Dormin ()
(+)-ABA ()
Abscisic Acid (Dormin) ()
(+)-ABSCISIC ACID ()
(S)?-?(+)?-?Abscisic acid ()
ABA ()
(+)-Abscisic Acid-d6 ()
P&D ID
PD021484
CAS
21293-29-8
721948-65-8
Tags
available
drug candidate
Drug Status
investigational
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Abscisic acid ((S)-(+)-Abscisic acid), an orally active phytohormone in fruits and vegetables, is an endogenously produced mammalian hormone. Abscisic acid is a growth inhibitor and can regulate many aspects of plant growth and development. Abscisic acid inhibits proton pump (H+-ATPase) and leads to the plasma membrane depolarization in a Ca2+-dependent manner. Abscisic acid, a LANCL2 natural ligand, is a potent insulin-sensitizing compound and has the potential for pre-diabetes, type 2 diabetes and metabolic syndrome[1][2].
PRICE 29
DESCRIPTION Potent TAOK inhibitor (Tocris Bioactive Compound Library)
DESCRIPTION Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
4
Compound Sets
6
Cayman Chemical Bioactives
10073
29093
DrugBank
DB16829
MedChem Express Bioactive Compound Library
HY-100560
Selleckchem Bioactive Compound Library
abscisic-acid-dormin
TargetMol Bioactive Compound Library
T6368
Tocris Bioactive Compound Library
6554
External IDs
46
Properties
(calculated by RDKit )
Molecular Weight
264.14
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
0
cLogP
2.25
TPSA
74.6
Fraction CSP3
0.47
Chiral centers
1.0
Largest ring
6.0
QED
0.61
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Proton Pump
Primary Target
Other Synthases/Synthetases
MOA
Agonist
Pathway
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Metabolism
Source data