General
Preferred name
AY-23578
Synonyms
11-deoxy-PGE1 ()
11-deoxy Prostaglandin E1 ()
11-deoxy-PGE1 ()
P&D ID
PD021209
CAS
37786-00-8
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
11-Deoxy prostaglandin E1 is a synthetic analog of PGE1. The Ki values for binding to the mouse EP1, EP2, EP3, and EP4 receptors are 600, 45, 1.1, and 23 nM, respectively.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
DrugMAP
EUbOPEN Chemogenomics Library
Guide to Pharmacology
Mcule NIBR MoA Box Subset
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
20
Molecular Weight
338.25
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
13
Ring Count
1
Aromatic Ring Count
0
cLogP
4.5
TPSA
74.6
Fraction CSP3
0.8
Chiral centers
3.0
Largest ring
5.0
QED
0.38
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
member
Recommended Cell Concentration
None
Source data
