General
Preferred name
MUSCIMOL
Synonyms
MUSCIMOL HYDROBROMIDE ()
[3H]muscimol ()
Pantherine ()
Agarin ()
NSC-333569 ()
Muscimol (CRM) ()
P&D ID
PD021173
CAS
2763-96-4
2489-10-3
18174-72-6
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Drug Status
investigational
Max Phase
Phase 1
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Potent GABAA agonist
(Tocriscreen Total)
DESCRIPTION
Highly potent and subtype-selective kainate agonist
(Tocris Bioactive Compound Library)
DESCRIPTION
GABA-A receptor agonist, water soluble
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
21
AdooQ Bioactive Compound Library
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugMAP
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
Ki Database
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
Mcule NIBR MoA Box Subset
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Tocris Bioactive Compound Library
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
51
Molecular Weight
114.04
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
1
cLogP
-0.16
TPSA
72.28
Fraction CSP3
0.25
Chiral centers
0.0
Largest ring
5.0
QED
0.53
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
GABA-A, GABA-C
Primary Target
GABAA Receptors
MOA
Agonist
GABA A receptor agonist
benzodiazepine receptor agonist
Member status
member
Target
GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRR1, GABRR2, GABRR3
Source data
