General
Preferred name
Leukotriene E4
Synonyms
LTE4 ()
Leukotriene E4-d5 ()
[3H]LTE4 ()
LEUKOTRIEN E4 ()
P&D ID
PD021016
CAS
75715-89-8
1240398-14-4
Tags
drug candidate
available
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Leukotriene E4 is a cysteinyl leukotriene produced by LTD4 and LTC4 in breath condensation, plasma, and urine. It is a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is the final product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, thus it can be used as an indicator in clinical diagnosis of asthma.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
BOC Sciences Bioactive Compounds
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugMAP
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Molecular Weight
439.24
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
4
Rotatable Bonds
18
Ring Count
0
Aromatic Ring Count
0
cLogP
4.31
TPSA
120.85
Fraction CSP3
0.57
Chiral centers
3.0
Largest ring
0.0
QED
0.14
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
