General
Preferred name
PD020898
Synonyms
2-ARACHIDONOYLGLYCEROL ()
2-Oarachidonoyl Glycerol ()
2-Arachidonoyl Glycerol ()
2-Arachidonoyl-Glycerol ()
P&D ID
PD020898
CAS
53847-30-6
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively).
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugMAP
Guide to Pharmacology
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
40
Molecular Weight
378.28
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
17
Ring Count
0
Aromatic Ring Count
0
cLogP
5.03
TPSA
66.76
Fraction CSP3
0.61
Chiral centers
0.0
Largest ring
0.0
QED
0.21
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Metabolic Enzyme/Protease
Neuronal Signaling
Target
Endogenous Metabolite
Cannabinoid Receptor
Source data
