General
Preferred name
SESAMIN
Synonyms
Fsesamin ()
Sesamin (Fagarol) ()
Fagarol, Fsesamin ()
P&D ID
PD020839
CAS
607-80-7
Tags
available
natural product
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Sesamin is a natural product that can be extracted from sesame seeds. It has been reported to have antihypertensive action, that is associated with inhibtion of CYP4F2-catalysed (20-hydroxyeicosatetraenoic acid) production . 20-HETE is a vasoactive and natriuretic eicosanoid.
(GtoPdb)
DESCRIPTION
Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2].
PRICE
42
DESCRIPTION
Sesamin is a selective delta 5 desaturase inhibitor in the biosynthesis of polyunsaturated fatty acids and is a lignan abundantly present in sesame oil. It has potent neuroprotective effects against cerebral ischemia.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
9
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2025/26
Drug Repurposing Hub
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
43
Molecular Weight
354.11
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
6
Aromatic Ring Count
2
cLogP
3.22
TPSA
55.38
Fraction CSP3
0.4
Chiral centers
4.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Stearoyl-CoA Desaturase (SCD)
MOA
NFkB pathway inhibitor
Pathway
Metabolic Enzyme/Protease
Source data
