General
Preferred name
TRAUMATIC ACID
Synonyms
Trans-2-Dodecenedioic Acid ()
P&D ID
PD020635
CAS
6402-36-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Traumatic Acid is a wound healing agent and a cytokinin (phytohormone). Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis[1][2].
PRICE 29
DESCRIPTION Traumatic Acid (Dodec-2-Enedioic Acid) is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective callus.
Compound Sets
3
Cayman Chemical Bioactives
88820
MedChem Express Bioactive Compound Library
HY-119358
Selleckchem Bioactive Compound Library
traumatic-acid
External IDs
23
Properties
(calculated by RDKit )
Molecular Weight
228.14
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
10
Ring Count
0
Aromatic Ring Count
0
cLogP
2.83
TPSA
74.6
Fraction CSP3
0.67
Chiral centers
0.0
Largest ring
0.0
QED
0.45
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Apoptosis
Reactive Oxygen Species (ROS)
Reactive Oxygen Species
Pathway
Immunology/Inflammation
Metabolic Enzyme/Protease
NF-κB
NF-¦ÊB
Source data