General
Preferred name
R-1 Methanandamide
Synonyms
METHANANDAMIDE ()
R-(+)-methanandamide ()
P&D ID
PD020613
CAS
157182-49-5
Tags
drug candidate
available
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
R-1 methanandamide is a potent cannabinoid (CB) receptor 1 agonist with selectivity for CB1 over CB2 receptors with Ki values ranging from 17.9 to 28.3 and 815 to 868 nM, respectively.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
Compound Sets
9
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugMAP
Guide to Pharmacology
Novartis Chemogenetic Library (NIBR MoA Box)
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Molecular Weight
361.3
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
16
Ring Count
0
Aromatic Ring Count
0
cLogP
5.63
TPSA
49.33
Fraction CSP3
0.61
Chiral centers
1.0
Largest ring
0.0
QED
0.28
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
virtual
MOA
LPAR1 agonists
Cannabinoid CB1 Agonists
"LPAR1 agonists
Cannabinoid CB1 Agonists"
Source data
