General
Preferred name
PD020581
Synonyms
19(R)-OH-PGE2 ()
19(R)-hydroxy Prostaglandin E2 ()
19(R)-OH-PGE2 ()
P&D ID
PD020581
CAS
64625-54-3
Tags
drug candidate
available
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
19(R)-Hydroxy-prostaglandin E2 is a PGE2 metabolite that acts as a potent smooth muscle relaxant and a selective EP2 receptor agonist, contrary to PGE2, which can activate a variety of prostanoid receptor types.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
DrugMAP
Guide to Pharmacology
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
15
Molecular Weight
368.22
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
4
Rotatable Bonds
12
Ring Count
1
Aromatic Ring Count
0
cLogP
2.22
TPSA
115.06
Fraction CSP3
0.7
Chiral centers
5.0
Largest ring
5.0
QED
0.31
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
