General
Preferred name
Prostaglandin J2
Synonyms
PGJ2 ()
PGJ2 ()
Prostaglandin J2-d4 ()
P&D ID
PD020572
CAS
60203-57-8
2738376-80-0
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Prostaglandin J2 (PGJ2) is a metabolite of PGD2, exhibiting antimitotic and antiproliferative effects. It inhibits platelet aggregation with IC50 value of 5-10 nM.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
BOC Sciences Bioactive Compounds
DrugMAP
Guide to Pharmacology
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
21
Molecular Weight
334.21
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
12
Ring Count
1
Aromatic Ring Count
0
cLogP
4.06
TPSA
74.6
Fraction CSP3
0.6
Chiral centers
3.0
Largest ring
5.0
QED
0.42
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
