General
Preferred name
lauric acid
Synonyms
N-Dodecanoic acid ()
Dodecylic acid ()
dodecanoic acid ()
dodecanoic acid, N-Dodecanoic acid, Dodecylic acid ()
DODECANOATE ()
Lauric Acid-d23 ()
Lauric Acid-13C ()
Lauric Acid-d2 ()
P&D ID
PD020396
CAS
143-07-7
59154-43-7
93639-08-8
64118-39-4
Tags
available
drug
Approved by
FDA
Drug indication
Discovery agent
Drug Status
approved
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 ¦Ìg/mL, respectively[1].
PRICE
29
DESCRIPTION
Lauric acid is the main acid in coconut oil and in palm kernel oil, and is believed to have antimicrobial properties. It might be used as an alternative treatment for antibiotic therapy of acne vulgaris. Lauric acid is used in the manufacture of soaps, detergents, cosmetics, and lauryl alcohol.
(Enamine Bioactive Compounds)
DESCRIPTION
Lauric Acid (Dodecylic acid),which is found naturally in various plant and animal fats and oils, is a saturated medium-chain fatty acid with a 12-carbon backbone. It is a major component of coconut oil and palm kernel oil.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
18
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
Enamine Bioactive Compounds
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
56
Molecular Weight
200.18
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
10
Ring Count
0
Aromatic Ring Count
0
cLogP
3.99
TPSA
37.3
Fraction CSP3
0.92
Chiral centers
0.0
Largest ring
0.0
QED
0.54
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
Endogenous Metabolite
GPR84, HNF4A, LTF, LY96, PLA2G2A, TLR4
MOA
bacterial permeability inducer
Pathway
Metabolism
Microbiology/virology
Anti-infection
Metabolic Enzyme/Protease
Source data
