General
Preferred name
FUMAGILLIN
Synonyms
NSC9168 ()
Amebacilin ()
Amebacilin,NSC9168 ()
(-)-fumagillin ()
Fumidil ()
NSC-9168 ()
ZGN-201 ()
P&D ID
PD020078
CAS
23110-15-8
127913-45-5
Tags
natural product
drug
available
Drug indication
Discovery agent
Drug Status
experimental
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
3
Organisms
0
Compound Sets
11
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
458.23
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
10
Ring Count
3
Aromatic Ring Count
0
cLogP
3.92
TPSA
97.89
Fraction CSP3
0.54
Chiral centers
6.0
Largest ring
6.0
QED
0.17
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
METAP2
antibiotic
HIV
Parasite
Antibiotics,Antineoplastic and Immunosuppressive Antibiotics
Member status
virtual
MOA
Methionine Aminopeptidase-2 (MetAP2) Inhibitors
Angiogenesis Inhibitors
Pathway
Anti-infection
Source data
