General
Preferred name
DZNep (hydrochloride)
Synonyms
3-deazaneplanocin A HCl ()
3-Deazaneplanocin A (hydrochloride) ()
NSC 617989 (hydrochloride) ()
3-Deazaneplanocin (hydrochloride) ()
3-deazaneplanocin A (DZNeP) HCl ()
P&D ID
PD019973
CAS
120964-45-6
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
3-deazaneplanocin A (DZNeP)HCl, an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
AdooQ Bioactive Compound Library
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
12
Molecular Weight
298.08
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
-0.37
TPSA
117.42
Fraction CSP3
0.33
Chiral centers
3.0
Largest ring
6.0
QED
0.56
Structural alerts
1
historic compounds (Chemical Probes.org)
Obsolete
Related compounds
Custom attributes
(extracted from source data)
Target
Histone methyltransferase
Orthopoxvirus
Pathway
Anti-infection
Epigenetics
Solubility
Soluble in DMSO, Methanol
Source data
