General
Preferred name
TRANS-ASARONE
Synonyms
¦Á-Asarone ()
α-Asarone ()
alpha-Asarone ()
.alpha.-Asarone ()
α-asarone ()
P&D ID
PD019678
CAS
2883-98-9
494-40-6
Tags
available
natural product
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION alpha-Asarone (¦Á-Asarone) is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.
PRICE 29
DESCRIPTION α-asarone is a pharmacologically active plant-derived phenylpropanoid compound. Studies in rodent models suggests that the noradrenergic (α1- and α2-adrenoceptors) and serotonergic (5-HT1A) pathways are involved in α-asarone's anti-depressant-like effects . (GtoPdb)
DESCRIPTION alpha-Asarone (trans-Asarone) is a psychoactive compound with antidepressant-like activity in mice. (TargetMol Bioactive Compound Library)
Compound Sets
8
Cayman Chemical Bioactives
11681
Drug Repurposing Hub
EU-OPENSCREEN Bioactive Compound Library
EOS100980
Guide to Pharmacology
13278
MedChem Express Bioactive Compound Library
HY-N0700
Novartis Chemogenetic Library (NIBR MoA Box)
Selleckchem Bioactive Compound Library
alpha-asarone
TargetMol Bioactive Compound Library
T3698
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
208.11
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
1
Aromatic Ring Count
1
cLogP
2.75
TPSA
27.69
Fraction CSP3
0.33
Chiral centers
0.0
Largest ring
6.0
QED
0.76
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
CYP2D6
CYP3A4
GABA Receptor
HMGCR
Member status
virtual
MOA
Acetylcholinesterase Inhibitors
HMG-CoA Reductase Inhibitors
cytochrome P450 inhibitor, HMGCR inhibitor
Pathway
Membrane Transporter/Ion Channel
Metabolism
Neuroscience
Neuronal Signaling
Source data