General
Preferred name
PD019530
Synonyms
3-deazaadenosine ()
3-Deazaadenosine (hydrochloride) ()
3-DZA HCl, c3Ado HCl ()
3-Deazaadenosine hydrochloride ()
P&D ID
PD019530
CAS
6736-58-9
86583-19-9
Tags
available
drug candidate
Drug indication
Arthritis
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 ¦ÌM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity.
DESCRIPTION
3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 ¦ÌM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity.
PRICE
262
DESCRIPTION
3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 ??M). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.
DESCRIPTION
3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 μM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
5
Organisms
1
Compound Sets
13
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
CZ-OPENSCREEN Bioactive Library
DrugBank
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
36
Molecular Weight
266.1
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
-1.38
TPSA
126.65
Fraction CSP3
0.45
Chiral centers
4.0
Largest ring
6.0
QED
0.53
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
HIV
HIV-1, A012 isolate
HIV-1, A018 isolate
S-adenosylhomocysteine hydrolase
Interleukins,TNF-alpha
Histamine Receptor
Pathway
Microbiology/virology
Proteases/Proteasome
Anti-infection
Source data
