General
Preferred name
d-AP5
Synonyms
D-APV ()
D-2-Amino-5-phosphonovaleric acid ()
P&D ID
PD019102
CAS
79055-68-8
76326-31-3
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
55
DESCRIPTION
The D-confirmation of AP5 is the more active isomer. This compoundis represented by ChEMBL without the charge (see link above).
(GtoPdb)
DESCRIPTION
Potent and selective NMDA antagonist; less active form of DL-AP5
(Tocris Bioactive Compound Library)
DESCRIPTION
D-AP5, a more active form of AP5, has been found to be an NMDA antagonist.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
D-AP5 (D-APV) is an NMDA receptor antagonist.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
AdooQ Bioactive Compound Library
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugMAP
Guide to Pharmacology
Mcule NIBR MoA Box Subset
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
197.05
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
4
Rotatable Bonds
5
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.64
TPSA
120.85
Fraction CSP3
0.8
Chiral centers
1.0
Largest ring
0.0
QED
0.43
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Neuroscience
Neuronal Signaling
Primary Target
NMDA Receptors
MOA
Antagonist
NMDA Antagonists
Member status
virtual
Target
NMDAR
iGluR
NMDA
Source data
