General
Preferred name
BAPTA
Synonyms
BAPTA tetrapotassium ()
DP-b99 metabolite ()
BAPTA tetrapotassium salt ()
P&D ID
PD018840
CAS
73630-08-7
85233-19-8
Tags
available
nuisance
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2].
PRICE
29
DESCRIPTION
BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
Cayman Chemical Bioactives
MedChem Express Bioactive Compound Library
Nuisance compounds in cellular assays
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
35
Molecular Weight
476.14
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
4
Rotatable Bonds
15
Ring Count
2
Aromatic Ring Count
2
cLogP
1.1
TPSA
174.14
Fraction CSP3
0.27
Chiral centers
0.0
Largest ring
6.0
QED
0.27
Structural alerts
1
Chelation
Cell-impermeable
Nuisance compounds
Related compounds
Custom attributes
(extracted from source data)
Target
Reactive Oxygen Species
Ca2+ chelator
Calcium Channel
Phospholipase
Pathway
NF-¦ÊB
Metabolic Enzyme/Protease
Immunology/Inflammation
Metabolism
NF-κB
Source data
